Both increase the exercise regulated gene for producing VGF a neuropeptide precursor. The administration of synthetic VGF-derived peptide produces a robust antidepressant effect in mice. Blocking the gene for VGF inhibited the effect of exercise and induced depressive-like behavior in the mice.
This information further supports the benefit of exercise and provides a novel target for the development of new antidepressants with a different mode of action than the ones now being used.
From Science Daily
What do exercise and electroconvulsive therapy have in common?
What do exercise and electroconvulsive therapy have in common?
What do exercise and electroconvulsive therapy have in common?
What do exercise and electroconvulsive therapy have in common?
Wednesday, January 23, 2008
What do exercise and electroconvulsive therapy have in common?
Posted by Dr. Shock at 5:34 PM
Labels: depression exercise genes electroconvulsive therapy electroshock
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