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Wednesday, December 5, 2007

Evidence Based Chocolate

Medbloggers do not significantly prefer dark chocolate above the inferior kinds of chocolate such as white chocolate and chocolate. This is the result of the poll: What kind of chocolate do you like? The hypothesis was that medbloggers like dark chocolate significantly more than other kinds of chocolate. Analysis was performed with Man-Huxley tests for categorical variables. Preference for dark chocolate was 10/17 (58%), chocolate 3/17 (17%) and white chocolate 4/17 (23%).

Nevertheless I am still convinced that someone with a Medblog prefers dark chocolate. This opinion is strengthened by another important publication in the British Medical Journal.

Parachute use to prevent death and major trauma related to gravitational challenge: systematic review of randomized controlled trials

Conclusions As with many interventions intended to prevent ill health, the effectiveness of parachutes has not been subjected to rigorous evaluation by using randomised controlled trials. Advocates of evidence based medicine have criticised the adoption of interventions evaluated by using only observational data. We think that everyone might benefit if the most radical protagonists of evidence based medicine organised and participated in a double blind, randomised, placebo controlled, crossover trial of the parachute.

Based on observational data I am convinced that Medbloggers are dark choclate users.

Related posts:
What kind of chocolate do you like? A Poll
What is the best evidence in evidence based medicine

Article Discussed
BMJ 2003;327:1459-1461 (20 December), doi:10.1136/bmj.327.7429.1459

Hazardous journey

Parachute use to prevent death and major trauma related to gravitational challenge: systematic review of randomised controlled trials

Gordon C S Smith, professor, Jill P Pell, consultant

Blogging on Peer-Reviewed Research
Thanks Eus


Boo Boo said...

Wait a minute... randomized controlled trials to prove that parachutes prevent death and major trauma related to gravitational challenge? So, the placebo people, they are the ones WITHOUT the parachutes, correct?

Let me guess - they send everyone out the airplane with what looks like a packed chute. Neither "patient" nor "coordinator" know if it's a real chute or a placebo chute (thus insuring it's double-blind). Only when the "patient" pulls the cord will they then know if they got the chute or the sugar. Unless the coordinators build the largest trampoline in the world, I don't see too many people willing to play Russian Roulette with parachutes.

PS: I happen to like Mexican chocolate - chocolate mixed with cinnamon, nutmeg and sometimes cream. Closest equivalent would be milk chocolate.

Aqua said...

I'm sharing this post with my pdoc...very funny, way to show that sometimes observation and experience help suggest the best course of action to take.

He and I have taken some chances on meds that may not necessarily be clearly evidence based for depression or mood stabilization, because he has seen patients helped by these meds.

Guess that's why I chose him to help me make choices about meds and not a dispensing machine:>) I'm glad he's willing to take chances to help me too.

You might be happy to hear we may have hit the right combination. (really hoping this is so)