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Saturday, September 15, 2007

Tamoxifen antimanic?

In an article on ScienceNews a placebo controlled trial with tamoxifen in 16 manic patients is described.
Tamoxifen is a Breast cancer drug.

Over a 3-week period, each individual was given either tamoxifen or a placebo. In a paper appearing online today in the journal Bipolar Disorders, the team reports that the tamoxifen-treated patients started improving by the 5th day, and five of the eight showed a 50% or more reduction of symptoms on a mania-rating scale--compared with only one of the eight in the placebo group.

In this article side-effects are not mentioned.

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